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Chronic fibrotic hypersensitivity pneumonitis

Imaging findings

CT scan shows progressive, upper-lobe predominant pulmonary fibrosis with extensive subpleural/paraseptal honeycombing and bronchiectasis. Explant pathology confirmed non-necrotizing granulomas and chronic HP.

Key takeaways

Chronic fibrotic HP can present with extensive upper-lobe predominant honeycombing that mimics UIP. Finding poorly-formed granulomas on pathology supports the diagnosis of HP over IPF.

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