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Hodgkin's Lymphoma with Mediastinal and Pulmonary Involvement

Hodgkin's Lymphoma with Mediastinal and Pulmonary Involvement▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Bulky, confluent lymphadenopathy was observed in the prevascular, paraortic, and AP window stations, predominantly affecting the anterior mediastinum, with additional bronchopulmonary and hilar lymphadenopathy. Lung windows showed a classic appearance of bilateral peribronchovascular dense nodular opacities with air bronchograms, without affecting the bronchovascular bundles. Post-treatment, the lesions showed significant resolution.

Key takeaways

This case presents a classic manifestation of Hodgkin's lymphoma, specifically with both extensive mediastinal lymphadenopathy and pulmonary involvement. Pulmonary involvement, seen in 15-17% of cases (most commonly in sclerosing type), typically appears as peribronchovascular nodular opacities and is generally very responsive to treatment.

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