CTICasesLow-Grade Mediastinal Liposarcoma
Imaging findings
Contrast-enhanced chest CT shows a large, predominantly fat-attenuating mass in the anterior and middle mediastinum. The mass is highly infiltrative, insinuating across multiple compartments and wrapping around major vascular structures, including the origin of the left subclavian artery, while containing very minimal soft tissue components.
Key takeaways
Low-grade mediastinal liposarcoma can closely mimic benign fatty lesions like lipomas or thymolipomas on CT due to its predominantly fat attenuation and lack of thick nodular septations. However, its highly infiltrative behavior, insinuating nature across multiple compartments, and encasement of major mediastinal vessels are key features pointing to a malignant liposarcoma.
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