CTICasesHypersensitivity Pneumonitis
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Imaging findings
The patient presented with respiratory distress linked to a specific work environment (salmon packing factory). Imaging findings included diffuse, smudgy, centrilobular ground-glass opacities that spared the immediate pleural surfaces, accompanied by evidence of mosaicism. Over time, the disease progressed to extensive fibrosis with a pattern pathologically consistent with a usual interstitial pneumonia (UIP).
Key takeaways
Hypersensitivity pneumonitis can present with distinctive centrilobular ground-glass nodules and, if the inciting exposure persists, can progress to irreversible fibrosis that mimics UIP. Detailed occupational history is critical for identifying potential external triggers that may precede the development of severe fibrotic disease.
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