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Miliary Coccidioidomycosis in AIDS Patient

Miliary Coccidioidomycosis in AIDS Patient▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph displays a diffuse miliary nodular pattern throughout both lungs, characterized by numerous small, millet-seed sized nodules. Corresponding CT images confirm a diffuse miliary pattern with one-millimeter cuts showing discrete, uniformly small nodules distributed bilaterally. Some calcified regional lymph nodes are noted.

Key takeaways

Miliary nodular patterns on chest imaging should prompt consideration of opportunistic infections, especially in immunocompromised patients like those with AIDS. Coccidioidomycosis can present with diffuse miliary disease and skin lesions. While less common than with histoplasmosis or tuberculosis, prior granulomatous infection may result in calcified lymph nodes.

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