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Infective Endocarditis with Patent Ductus Arteriosus

Imaging findings

CT angiography shows severe thickening, vegetations, and perforation of the aortic and mitral valves. A patent ductus arteriosus (PDA) is identified, showing localized wall thickening and irregular contours suggestive of mycotic involvement.

Key takeaways

In patients with a PDA, turbulent blood flow across the shunt can damage the endothelial lining of the pulmonary artery or ductus, creating a nidus for infective endocarditis (endarteritis). The infection can subsequently seed the aortic and mitral valves, presenting as persistent, multi-valvular endocarditis.

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