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Eosinophilic Granulomatosis with Polyangiitis

Imaging findings

High-resolution chest CT demonstrates pronounced, diffuse bronchial wall thickening without significant bronchiectasis or mucous impaction. Laboratory evaluation reveals peripheral blood eosinophilia, and the patient has a history of severe asthma and fleeting pulmonary opacities on prior imaging.

Key takeaways

Eosinophilic Granulomatosis with Polyangiitis (EGPA, formerly Churg-Strauss syndrome) is a systemic small-to-medium vessel vasculitis characterized by asthma, transient pulmonary infiltrates, and peripheral eosinophilia. Bronchial wall thickening can be an early or dominant airway manifestation of the disease, often preceding other classic features such as fleeting pulmonary infiltrates.

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