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Mediastinal Paraganglioma

Imaging findings

Chest CT shows an avidly enhancing mass in the pretracheal region extending through the aortopulmonary (AP) window, with extensive collateral/parasitic feeding vessels. MIBG scan shows heterogeneous/partial tracer uptake, and catecholamine levels are mildly elevated.

Key takeaways

Mediastinal paraganglioma is a highly vascular neuroendocrine tumor arising from paraganglia. It typically presents as a strongly enhancing mass in the middle or anterior mediastinum, with potential for catecholamine secretion and MIBG avidity.

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