CTICasesSevere Granulomatosis with Polyangiitis (GPA) with Airway and Sinus Involvement
Imaging findings
Chest radiograph shows multiple bilateral parenchymal opacities. CT demonstrates severe tracheal involvement with mucosal ulcerative sloughing and narrowing, typical parenchymal opacities, and severe sinus disease. Stenosis of the left upper lobe bronchus also developed.
Key takeaways
Severe Granulomatosis with Polyangiitis (GPA) can manifest with extensive airway involvement including mucosal ulceration and sloughing, leading to stenosis over time. Sinus disease and typical parenchymal findings are also characteristic. Correlation of these widespread findings points to aggressive GPA.
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