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Cardiac transthyretin amyloidosis

Imaging findings

Cardiac MRI shows left ventricular hypertrophy with diffuse late gadolinium enhancement involving both the subendocardium and the mid-myocardium of the septum and lateral wall.

Key takeaways

Transthyretin cardiac amyloidosis typically presents with more pronounced myocardial hypertrophy and a more transmural or patchy mid-wall enhancement pattern compared to the predominantly subendocardial enhancement of light chain amyloidosis.

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