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BiPAP-Induced Pneumopericardium and Pneumomediastinum

Imaging findings

CT chest in a non-intubated COVID-19 patient receiving non-invasive positive pressure ventilation (BiPAP) shows extensive pneumomediastinum and pneumopericardium without evidence of esophageal rupture.

Key takeaways

Barotrauma (alveolar rupture leading to the Macklin effect) is well-known in mechanical ventilation but can also occur with non-invasive ventilation (BiPAP/CPAP). The positive pressure can dissect air into the mediastinum and pericardial space, especially in diseased lungs with reduced compliance.

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