CTICasesDystrophic Lymph Node Calcification in Small Cell Lung Cancer
Imaging findings
Serial chest CT scans of a patient with extensive small cell lung cancer demonstrate a rapid reduction in the size of mediastinal and hilar lymphadenopathy following chemotherapy, accompanied by the rapid deposition of dense, dystrophic calcification within the responding nodes.
Key takeaways
Small cell lung cancer is highly chemo-sensitive, and a rapid tumor response can lead to extensive tissue necrosis and subsequent dystrophic calcification. While nodal calcification is classically associated with treated lymphoma, treated mucinous adenocarcinoma, or granulomatous disease, it can also occur as a sign of rapid therapeutic response in small cell lung cancer.
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