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Myocardial Lipomas in Tuberous Sclerosis Complex

Myocardial Lipomas in Tuberous Sclerosis Complex▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Abdominal CT slices demonstrate multiple solid masses in both kidneys consistent with angiomyolipomas, confirming a clinical diagnosis of tuberous sclerosis. Thoracic CT shows multiple small, non-enhancing fatty masses throughout the myocardium, including the right ventricle and the lateral to anterolateral wall of the left ventricle. High-resolution chest CT also reveals scattered, thin-walled cysts characteristic of mild lymphangioleiomyomatosis.

Key takeaways

Cardiac fat deposits or lipomas are a recognized manifestation of tuberous sclerosis complex. These benign lesions typically behave like lipomas, containing pure fat without soft-tissue enhancement, and must be distinguished from other cardiac tumors or rhabdomyomas. Radiologists should routinely inspect the myocardium for these fatty lesions when imaging patients with known tuberous sclerosis.

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