CTICases ← All cases

Cryptococcus Pulmonary Nodule in CVID

Imaging findings

CT chest shows a vague, solid nodule in the left apex, which has remained persistent over several weeks, associated with minimal surrounding reactive changes. The patient had common variable immunodeficiency (CVID) and biopsy confirmed Cryptococcus infection.

Key takeaways

Common variable immunodeficiency (CVID) predisposes patients to atypical infections. Cryptococcus neoformans can present as a solitary, stable pulmonary nodule, mimicking primary lung cancer. In CVID patients, tissue biopsy or direct antigen testing is essential for diagnosis as serology can be false-negative.

AI-assisted summary — may contain errors. Verify against the source video. Learn more

More from this webinar

See all cases from November 9, 2021 →

Related Infection cases

Browse all Infection cases →