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Pulmonary Artery Sarcoma

Imaging findings

A patient with persistent filling defects in the pulmonary arteries underwent anticoagulation, yet the defects persisted and were associated with new, resolving clots. Surgical resection revealed extensive intimal soft tissue tumor growth, identified as sarcoma.

Key takeaways

Pulmonary artery sarcomas often present with findings that mimic chronic thromboembolic disease. The presence of non-resolving, heaped-up intimal soft tissue is a key discriminator for tumor versus simple thrombus.

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