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Lipomatous Hypertrophy of the Interatrial Septum compressing the SVC

Imaging findings

CT chest shows extensive fat-density tissue (lipomatosis) within the interatrial septum and atrial walls, extending superiorly to cause significant extrinsic compression and narrowing of the superior vena cava (SVC).

Key takeaways

Lipomatous hypertrophy of the interatrial septum (LHIS) is a benign deposition of brown fat in the interatrial septum, typically sparing the fossa ovalis (giving it a characteristic dumbbell shape). While usually asymptomatic, extensive lipomatous deposition can cause mass effect, compressing the SVC or leading to cardiac arrhythmias.

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