CTICasesSynthetic Cannabinoid-Induced Bronchiolitis
Imaging findings
Serial chest radiographs taken two days apart demonstrate the acute development of subtle, diffuse reticular or branching opacities. Subsequent chest CT confirms a diffuse, profuse, bilateral "tree-in-bud" or bronchiolar pattern with prominent bronchial and bronchiolar wall thickening throughout all lung zones, without large pulmonary artery enlargement.
Key takeaways
Diffuse bronchiolar tree-in-bud patterns can occur rapidly following inhalation exposure to toxic agents, such as synthetic cannabinoids. Although similar patterns can be seen with infectious bronchopneumonia or intravenous excipient lung disease, the rapid onset, prominent airway thickening, and lack of pulmonary hypertension can favor toxic inhalation.
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