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Tracheal Diverticula in Cystic Fibrosis post-Transplant

Imaging findings

Serial CT scans in a patient with cystic fibrosis show multiple small, gas-filled mucosal outpocketings along the posterior wall of the trachea (tracheal/bronchial diverticula) that persist and slowly enlarge following bilateral lung transplantation.

Key takeaways

Tracheal and bronchial diverticula occur in up to 60% of cystic fibrosis patients, arising from chronic high expiratory pressures and mucosal gland dilatation. Following lung transplantation, these native airway diverticula persist and can serve as a reservoir for bacterial colonization and recurrent donor lung infection.

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