CTICasesPulmonary Fibrosis in Scleroderma
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Imaging findings
Honeycombing and reticulation with volume loss, notably with an anterior distribution in the upper lobes and posterior distribution in the lower lobes.
Key takeaways
The "four corner sign" in patients with collagen vascular disease, such as scleroderma, describes a characteristic distribution of fibrosis/honeycombing, which should prompt consideration of underlying connective tissue disease.
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