Radiation Fibrosis
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Imaging findings
A patient with a history of total body radiation for leukemia presented with diffuse pulmonary abnormalities. CT showed progression from ground-glass opacities to extensive, peri-bronchovascular consolidation and fibrosis. The fibrosis was extensive throughout the lungs, consistent with diffuse radiation-induced lung disease.
Key takeaways
Radiation-induced lung disease can manifest as extensive fibrosis and consolidation in the absence of lung shielding during total body irradiation. It should be considered in patients with a history of whole-lung radiation therapy.
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