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Swyer-James-MacLeod Syndrome

Imaging findings

Chest CT shows bilateral, asymmetric lung abnormalities, including extensive bronchial wall thickening, bronchiectasis, and mosaic attenuation with areas of hyperlucent lung and decreased vascular caliber. There is also a left lower lobe lung abscess and associated pleural effusion.

Key takeaways

Swyer-James-MacLeod syndrome is an acquired post-infectious form of constrictive bronchiolitis obliterans that occurs following childhood viral infections (such as adenovirus or RSV). It is characterized by unilateral or asymmetric hyperlucent lung tissue, air trapping on expiration, and secondary pulmonary artery hypoplasia/oligemia. Although classically described as unilateral, it is frequently a bilateral, asymmetric process.

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