CTICasesCostochondral Junction Chondrosarcoma (Two Cases)
Imaging findings
Two separate patients presenting within a month of each other had similar-appearing rib-based masses arising at or near the costochondral junction with irregular, elevated cortex and an internal bone/cartilaginous matrix; the first patient (a 68-year-old woman found incidentally) also had a pleural effusion with metastatic tumor deposits along the pleura and diaphragm. Both masses were biopsy-proven low-grade chondrosarcoma.
Key takeaways
Chondrosarcoma is the most common primary malignant rib neoplasm and classically arises at or near the costochondral junction in middle-aged patients, with an internal chondroid/osseous matrix and cortical irregularity distinguishing it from benign entities like fibrous dysplasia or aneurysmal bone cyst; low-grade chondrosarcoma, even with pleural metastatic deposits, may be managed with watchful observation rather than immediate systemic therapy per multidisciplinary tumor board decision.
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