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Mediastinal Dedifferentiated Liposarcoma

Imaging findings

Chest radiograph and CT show a massive, encapsulated middle/posterior mediastinal mass displacing the esophagus to the left. The mass has internal dystrophic calcifications and few fatty elements. It grew rapidly over two years.

Key takeaways

Dedifferentiated liposarcoma can arise in the mediastinum, presenting as a giant, encapsulated mass with calcification. Because they contain very little fat, they can be difficult to distinguish from other mediastinal sarcomas or leiomyomas.

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