CTICasesMesalamine-Induced Organizing Pneumonia
Imaging findings
Chest CT of a patient with inflammatory bowel disease on mesalamine shows multifocal, sharply marginated consolidations, ground-glass opacities, and focal crazy-paving. The lesions cleared completely four weeks after stopping mesalamine and starting steroids.
Key takeaways
Mesalamine (5-ASA) can induce pulmonary toxicity, classically presenting as an organizing pneumonia or eosinophilic pneumonia pattern with prominent lobular restriction or crazy-paving.
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