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Epithelioid Hemangioendothelioma

Imaging findings

PET/CT shows multiple FDG-avid lesions scattered throughout the lungs, mediastinal lymph nodes, liver, and bones, which progressed rapidly on follow-up imaging. Biopsy was positive for vascular markers.

Key takeaways

Epithelioid hemangioendothelioma (EHE) is a rare, malignant vascular neoplasm of endothelial origin. It can be indolent but occasionally behaves aggressively. Staging typically shows multicentric disease involving the lungs, liver, and bones, and is more common in females.

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