CTICasesPericardial Granulocytic Sarcoma
Imaging findings
CT chest in a patient with myelodysplastic syndrome shows circumferential, soft-tissue density infiltration in the pericardial space surrounding the coronary arteries, associated with pleural effusion. Follow-up CT one month after chemo-radiation shows complete resolution.
Key takeaways
Granulocytic sarcoma (chloroma or extramedullary myeloid tumor) is a rare manifestation of myelodysplastic syndrome or AML. It can infiltrate the pericardial space, mimicking lymphoma or mesothelioma, but is highly radiosensitive and chemo-sensitive, showing dramatic rapid resolution.
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