Pulmonary Xanthogranulomatous Inflammation
Imaging findings
A contrast-enhanced chest CT demonstrates a newly developed, thick-walled cavitary mass in the right upper lobe of a liver and kidney transplant patient with a history of Klebsiella urinary tract sepsis.
Key takeaways
Xanthogranulomatous inflammation is a chronic, benign inflammatory process characterized by an abundance of lipid-laden macrophages and Touton giant cells. Although most commonly seen in the kidneys or gallbladder, xanthogranulomatous disease can rarely occur in the lungs, typically as a walled-off, chronic inflammatory reaction triggered by recurrent or persistent bacterial infections such as Klebsiella.
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