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Anti-Synthetase Syndrome

Imaging findings

Variable patterns of interstitial lung disease, including organizing pneumonia (with reverse halo sign) and fibrotic NSIP (non-specific interstitial pneumonia).

Key takeaways

Anti-synthetase syndrome (often associated with Jo-1 or PL-7 antibodies) encompasses a spectrum of lung injury from acute organizing pneumonia to chronic fibrosis.

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