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Chronic Hypersensitivity Pneumonitis (Byssinosis)

Imaging findings

High-resolution chest CT shows a bronchocentric distribution of fibrosis, including bronchial wall thickening, reticulation, architectural distortion, and areas of lobular air trapping. Surgical lung biopsy confirmed poorly formed, non-necrotizing granulomas.

Key takeaways

Byssinosis is an occupational lung disease caused by prolonged inhalation of cotton, flax, or hemp dust. While acutely characterized by chest tightness on the first day of the workweek (commonly referred to as Monday fever), long-term exposure can lead to chronic fibrotic hypersensitivity pneumonitis.

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