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Daptomycin-Induced Eosinophilic Pneumonia

Imaging findings

Chest CT shows bilateral, peripheral-predominant ground-glass consolidations with a reversed halo (atoll) sign and crazy-paving. The findings resolved rapidly within one month after discontinuing daptomycin.

Key takeaways

Daptomycin-induced acute eosinophilic pneumonia is a rare drug reaction. It manifests radiographically with peripheral organizing pneumonia/consolidation patterns and crazy paving, which resolve promptly after drug cessation.

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