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IgG4-related lung disease complicated by systemic air embolism

Imaging findings

CT shows stable, peribronchial consolidated masses in the right lung. Post-biopsy CT demonstrates massive systemic air embolism with air layering in the left atrium and left ventricle, causing cerebral infarctions. Pathology confirmed IgG4-related lung disease.

Key takeaways

IgG4-related lung disease can manifest as chronic mass-like peribronchial consolidation. Transthoracic needle biopsy of central lesions carries a risk of systemic air embolism if a pulmonary vein and airway are concurrently punctured.

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