CTICasesProgressive Centrilobular Emphysema
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Imaging findings
CT chest shows a significant progression over a four-year interval of diffuse centrilobular emphysema, characterized by multiple small, round, wall-less areas of lucency. There is also associated reticulation, traction bronchiectasis, and progressive dependent ground-glass opacities in the lung bases.
Key takeaways
Centrilobular emphysema is a smoking-related lung disease that can continue to progress over time even after smoking cessation. While the presence of basilar ground-glass and reticular opacities can sometimes suggest a superimposed interstitial pattern like desquamative interstitial pneumonia (DIP) or non-specific interstitial pneumonia (NSIP), clinicians should also consider cardiac congestion or simple progression of emphysema with architectural distortion.
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