Silicosis
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Imaging findings
A chest radiograph (2014) shows upper lobe predominant, fairly symmetric nodules, some hilar elevation, and upper lobe volume loss. CT (2014 and more recent) shows coalescent, discrete, well-defined, and dense nodules in a perilymphatic distribution, congregating along pleural surfaces to form "pseudo plaques," with some conglomerate fibrosis in the left upper lobe and emphysema.
Key takeaways
Silicosis typically presents with discrete, rounded, well-defined, and dense perilymphatic nodules, often coalescing into thick pseudo plaques, and can progress to conglomerate fibrosis. It primarily affects the upper lobes. An occupational history (e.g., 50 years as a bricklayer) is crucial for diagnosis and helps differentiate it from sarcoidosis, which often has less discrete, more irregular nodules.
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