CTICasesAmiodarone Pulmonary Toxicity
Imaging findings
CT chest shows progressive, dense consolidations in the bilateral lungs. Non-contrast CT demonstrates high attenuation within the consolidations and markedly high attenuation in the liver (96 HU).
Key takeaways
Amiodarone is an iodine-rich drug that accumulates in macrophages, presenting on non-contrast CT as high attenuation in the liver, spleen, and pulmonary consolidations. Acute amiodarone toxicity can present as progressive respiratory failure from organizing pneumonia or DAD.
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