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Sulfasalazine-Induced Organizing Pneumonia

Imaging findings

CT chest shows migratory peripheral consolidations with reverse halo signs (atoll sign). The patient has ulcerative colitis and was treated with sulfasalazine. Separate congenital findings include a high origin of the left main coronary artery above the sinus, and a meandering right upper lobe pulmonary vein.

Key takeaways

Sulfasalazine is a well-known cause of drug-induced lung injury, classically presenting as migratory organizing pneumonia with atoll signs. In this patient, the acute drug reaction co-existed with incidental congenital cardiac and venous anomalies, highlighting the importance of separate diagnoses.

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