CTICasesSulfasalazine-Induced Organizing Pneumonia
[...]. Sulfasalazine-Induced Organizing Pneumonia. CTICases. Published December 17, 2019. https://cticases.com/c/srq9j
Imaging findings
CT chest shows migratory peripheral consolidations with reverse halo signs (atoll sign). The patient has ulcerative colitis and was treated with sulfasalazine. Separate congenital findings include a high origin of the left main coronary artery above the sinus, and a meandering right upper lobe pulmonary vein.
Key takeaways
Sulfasalazine is a well-known cause of drug-induced lung injury, classically presenting as migratory organizing pneumonia with atoll signs. In this patient, the acute drug reaction co-existed with incidental congenital cardiac and venous anomalies, highlighting the importance of separate diagnoses.
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