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Undifferentiated Pleural Sarcoma with Rib Destruction

Undifferentiated Pleural Sarcoma with Rib Destruction▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

An initial chest radiograph in 2007 was called normal. In 2012, a radiograph showed subtle periosteal reaction and destruction of a rib. CT revealed an extensive lesion involving two contiguous ribs with periosteal reaction and permeation.

Key takeaways

The case highlights the subtlety of bone destruction on initial radiographs. The lesion was an undifferentiated sarcoma, which eventually led to brain metastases. Malignant pleural lesions like sarcomas or aggressive fibrous tumors can erode into bone, differentiating them from benign fibrous tumors.

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