CTICasesInvasive Pulmonary Mucormycosis
Imaging findings
CT of the chest demonstrates a rapidly growing, large, ill-defined mass with a "bird's nest" (reversed halo) sign, characterized by a rim of peripheral consolidation, central ground-glass attenuation with relative lucency, and direct tissue invasion across the major fissure.
Key takeaways
Invasive pulmonary mucormycosis is an aggressive fungal infection in neutropenic patients that expands rapidly and crosses tissue planes. It classically presents with the "bird's nest" or reversed halo sign. Rapid diagnosis by tissue biopsy is crucial, as standard bronchoalveolar lavage may yield unrelated organisms (such as Actinomyces) and delay the initiation of appropriate therapies like amphotericin B.
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