CTICasesSeasonal Human Coronavirus Pneumonia
Imaging findings
Inspiratory CT demonstrates preexisting findings of small airways disease (mosaic attenuation and air trapping) with new, superimposed, widespread, upper-lung-predominant ground-glass opacities.
Key takeaways
In severely immunocompromised hosts, such as post-stem cell transplant recipients, seasonal (non-SARS-CoV-2) human coronaviruses can cause life-threatening lower respiratory tract infections and pneumonitis. These present with extensive ground-glass opacities that mimic other opportunistic infections. Seasonal viral outbreaks may occur in delayed, atypical summer cycles due to shifts in community immunity.
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