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Disseminated Blastomycosis

Imaging findings

Older man with a kidney transplant presented with a fever, shortness of breath, cough, and pustular skin lesions. Chest radiograph demonstrated a generous heart, multiple lung nodules, and a loculated pleural effusion. CT findings included large nodules, micronodules, septal thickening, and dense consolidation, with a conspicuous absence of lymphadenopathy.

Key takeaways

Blastomycosis should be considered in immunocompromised patients, particularly those with compatible travel or exposure history (such as northern Wisconsin), even in the absence of CNS or bone involvement.

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