CTICasesDaptomycin-Induced Lung Toxicity
Imaging findings
Patient treated with daptomycin for a cutaneous infection developed shortness of breath. Radiograph and CT showed peripheral consolidation, reticulation with lower lobe predominance, air bronchograms, and some dilated airways, consistent with a mixed organizing pneumonia and NSIP pattern.
Key takeaways
Daptomycin is a known cause of pulmonary toxicity, which may manifest as a mixed organizing pneumonia and NSIP pattern on imaging. The condition can be reversible with drug cessation and corticosteroids.
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