CTICasesAdenocarcinoma in Chronic Hypersensitivity Pneumonitis
Imaging findings
CT chest shows a background of chronic hypersensitivity pneumonitis with subpleural honeycombing, ground-glass opacities, and mosaic attenuation. A solid, growing upper lobe mass is present, which was biopsy-proven to be adenocarcinoma.
Key takeaways
Chronic hypersensitivity pneumonitis (such as from domestic down duvet exposure) causes progressive pulmonary fibrosis. Similar to other fibrotic lung diseases (like IPF), chronic HP predisposes to the development of pulmonary malignancies, typically adenocarcinoma, requiring careful screening of new or growing nodules.
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