CTICasesSpontaneous Thrombosis of Bronchopulmonary Sequestration
Imaging findings
CT of the chest in a patient with sickle cell disease shows a hyper-inflated left lower lobe region with a pleural outline (bronchial atresia variant) and a persistent consolidative segment. Contrast-enhanced CT reveals a small, calcified vascular nubbin arising from the descending thoracic aorta, representing a chronically thrombosed and occluded systemic feeding artery supplying a bronchopulmonary sequestration.
Key takeaways
Bronchopulmonary sequestration is a congenital lung anomaly characterized by a segment of non-functioning lung tissue that lacks normal connection to the tracheobronchial tree and receives systemic arterial supply, typically from the descending aorta. In patients with sickle cell disease, the hypercoagulable state and microvascular vaso-occlusive crises can lead to spontaneous thrombosis of the systemic feeding artery, resulting in auto-infarction and involution of the sequestration.
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