Granulomatosis with Polyangiitis with Peribronchovascular Consolidation
Imaging findings
High-resolution chest CT shows progressive bilateral peribronchovascular and perilobular nodular consolidation, marked bronchial wall thickening, and centrilobular nodules. There is also mild, ill-defined hilar and mediastinal lymphadenopathy representing reactive lymphoid enlargement.
Key takeaways
Granulomatosis with polyangiitis can present with atypical, airway-centered, and perilobular patterns of consolidation mimicking organizing pneumonia, infection, or lymphoma. This presentation is often associated with pronounced bronchial wall thickening and may occur even in patients who are ANCA-negative, requiring biopsy for definitive diagnosis.
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