CTICasesMultiple Myeloma with Pathologic Compression Fractures and Plasmacytoma
Imaging findings
Portable radiograph shows chronic rib fractures and lumpy, bumpy paravertebral stripes. Comparison to prior imaging shows new compression fractures in the midthoracic spine. MRI confirms diffuse marrow replacement, new pathologic compression fractures, and cord narrowing due to plasmacytoma (multiple myeloma progression), not hematoma.
Key takeaways
Subtle radiographic findings on portable chest X-rays, especially abnormal paravertebral stripes and new compression fractures, should prompt further investigation with a relevant clinical history (bilateral rib pain, no trauma). In patients with multiple myeloma, rapid progression of plasmacytoma can lead to new pathologic fractures and cord narrowing, explaining neurological symptoms.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Mediastinal Synovial Cell SarcomaNeoplastic
- Anterior Mediastinal Mature Teratoma with Anti-NMDA Receptor Encephalitis (Paraneoplastic Syndrome)Neoplastic
- Post-Primary Tuberculosis with Concurrent AdenocarcinomaInfection
- Sarcoidosis with Pseudo-Plaque PatternAutoimmune
- Rapidly Progressing Disseminated Adenocarcinoma Mimicking TuberculosisNeoplastic
- Hypertrophic Cardiomyopathy with Systolic Anterior Motion (SAM) of the Mitral ValveCongenital
- Acquired Left Lower Lobe Bronchial Angulation and Recurrent AspirationInflammatory
- Left Hemidiaphragm Paralysis due to Phrenic Nerve Injury (Iatrogenic)Iatrogenic
See all cases from August 5, 2016 →