CTICasesBenign Metastasizing Leiomyoma
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Imaging findings
CT scans performed at different times revealed multiple small pulmonary nodules, particularly in the lower chest. Immunohistochemical analysis of these nodules showed strong staining for progesterone and some staining for estrogen receptor. A previous pelvic ultrasound did not identify an obvious uterine fibroid.
Key takeaways
This is an interesting case of benign metastasizing leiomyoma, a rare entity where morphologically benign smooth muscle tumors appear in the lung, often originating from uterine fibroids. While typically seen in women with a history of uterine fibroids or gynecologic surgery, this case highlights that an obvious fibroid may not always be present. The positivity for estrogen and progesterone receptors on immunophenotyping is a characteristic feature, aiding in the diagnosis and differentiating it from malignant neoplasms.
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