CTICasesToxoplasmosis Lymphadenopathy in a Heart Transplant Recipient
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Imaging findings
A chest x-ray was interpreted as normal. CT scan, however, showed modest but strongly enhancing lymphadenopathy in both axillae and the mediastinum. There were no distinctive lung parenchymal findings.
Key takeaways
Toxoplasmosis can manifest as lymphadenopathy, with cervical lymph nodes being the most common presentation, followed by mediastinal and axillary involvement. In immunocompromised patients, such as heart transplant recipients, fever and lymphadenopathy should prompt consideration of toxoplasmosis. Diagnosis was confirmed by biopsy of a mediastinal lymph node. While often associated with cats, Toxoplasma gondii can be harbored by many animals, and transmission can occur through various routes.
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