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Marijuana-Induced Paraseptal Emphysema

Imaging findings

Chest CT in a 20-year-old male never-smoker of tobacco demonstrates prominent subpleural and fissural paraseptal emphysema (small, uniform subpleural cysts) with relative sparing of the rest of the lungs. The patient has a history of heavy marijuana use.

Key takeaways

Paraseptal emphysema can occur in young, non-tobacco smoking individuals due to heavy inhalation of marijuana smoke. This may relate to deep inspiratory maneuvers and breath-holding, and increases the risk of spontaneous pneumothorax.

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