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Unicentric Castleman's Disease (Mediastinal/Hilar)

Unicentric Castleman's Disease (Mediastinal/Hilar)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A large, very vascular, and intensely enhancing opacity is identified in the mediastinum, specifically in the subcarinal region. CT demonstrates prominent, fat bronchial arteries actively supplying the mass. A chest radiograph reveals a large fullness in the azygo-esophageal recess, corresponding to the mediastinal mass.

Key takeaways

This case provides another excellent example of unicentric Castleman's disease, emphasizing its highly vascular nature. The recruitment of significantly enlarged bronchial arteries is a hallmark feature. Radiographs can show non-specific mediastinal widening or fullness, requiring CT for detailed characterization of the lesion's vascularity and location.

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