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Basal-Predominant Pneumocystis jirovecii Pneumonia (PJP)

Imaging findings

CT scans of the chest show a progressive, extensive ground-glass lung abnormality that is strongly and atypically concentrated in the lung bases, mimicking aspiration or pulmonary edema.

Key takeaways

Although Pneumocystis jirovecii pneumonia (PJP) typically manifests as a symmetric, upper- or mid-lung predominant process, atypical distributions such as basal-predominant ground-glass opacities can occur. PJP should be considered in any patient presenting with chronic diarrhea, progressive dyspnea, and profound lymphopenia, as these symptoms frequently represent the initial presentation of HIV/AIDS.

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