CTICasesSarcoidosis (with prominent pseudo plaques)
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Imaging findings
CT shows large, peripheral pseudo plaques along the pleural surfaces, some with faint calcification, appearing thick and chunky. Lymphadenopathy is also present. Radiographs show nodules in the periphery that appear less conspicuous on follow-up, suggesting regression.
Key takeaways
Sarcoidosis can also present with prominent pseudo plaques and lymphadenopathy, sometimes mimicking silicosis. However, sarcoid plaques are often less discrete, less dense, and can regress over time. The etiology of sarcoidosis may involve different inhaled antigens, leading to varied imaging patterns (e.g., peribronchovascular vs. subpleural). Skin biopsy can confirm granulomatous inflammation. Some sarcoid patterns, particularly 'alveolar sarcoid' in African American patients, can show large lesions that melt away.
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